PMID

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Article Title

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Calcium channel blocking and positive inotropic activities of ethyl 5-cyano-1,4-dihydro-6-methyl-2-[(phenylsulfonyl)methyl]-4-aryl-3- pyridine-carboxylate and analogues. Synthesis and structure-activity relationships.

Warner-Lambert

Dihydropyrimidines: novel calcium antagonists with potent and long-lasting vasodilative and antihypertensive activity.

Suntory Institute For Biomedical Research

2-(2-Aryl-2-oxoethylidene)-1,2,3,4-tetrahydropyridines. Novel isomers of 1,4-dihydropyridine calcium channel blockers.

Warner-Lambert

Stereoselectivity of a potent calcium antagonist, 1-benzyl-3-pyrrolidinyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

TBA

Synthesis and biological activity of the calcium modulator (R) and (S)-3-methyl 5-pentyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate.

Fourth Military Medical University

 

(cis)-3-methyl-1,5-benzothiazepine-4-ones: potent analogs of the calcium channel blocker diltiazen

TBA

New purines and purine analogs as modulators of multidrug resistance.

Institut De Recherches Servier

Cyclocurcumin, an Antivasoconstrictive Constituent of Curcuma longa (Turmeric).

Seoul National University

Asymmetric synthesis and biological evaluations of (+)- and (-)-6-dimethoxymethyl-1,4-dihydropyridine-3-carboxylic acid derivatives blocking N-type calcium channels.

Ajinomoto Pharmaceuticals

Stereoselective behavior of the functional diltiazem analogue 1-[(4-chlorophenyl)sulfonyl]-2-(2-thienyl)pyrrolidine, a new L-type calcium channel blocker.

Universita Degli Studi Di Perugia

L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives.

Universita Degli Studi Di Bologna

Discovery of novel and cardioselective diltiazem-like calcium channel blockers via virtual screening.

Universit£

The structure-activity relationship study on 2-, 5-, and 6-position of the water soluble 1,4-dihydropyridine derivatives blocking N-type calcium channels.

Ajinomoto

Simplified tetrandrine congeners as possible antihypertensive agents with a dual mechanism of action.

Universidad De Chile

Structure-activity relationship study of 1,4-dihydropyridine derivatives blocking N-type calcium channels.

Ajinomoto

Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke.

Boehringer Ingelheim Pharma

Vasorelaxation by new hybrid compounds containing dihydropyridine and pinacidil-like moieties.

National Academy of Sciences of Ukraine

Identification of a dihydropyridine as a potent alpha1a adrenoceptor-selective antagonist that inhibits phenylephrine-induced contraction of the human prostate.

New York University Medical Center

Terpenoids with vasorelaxant effects from the Chinese liverwort Scapania carinthiaca.

Shandong University

Benzazepinone calcium channel blockers. 4. Structure-activity overview and intracellular binding site.

Bristol-Myers Squibb Pharmaceutical Research Institute